BDBM50061251 1-(3,4-Dichloro-phenyl)-2-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)-ethanol::CHEMBL127013

SMILES: OC(CN1C2CCC1CC(C2)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=CDDODAHZNGOHJP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061251 (1-(3,4-Dichloro-phenyl)-2-(3-phenyl-8-aza-bicyclo[...) Show SMILES OC(CN1C2CCC1CC(C2)c1ccccc1)c1ccc(Cl)c(Cl)c1 |TLB:11:9:3:5.6| Show InChI InChI=1S/C21H23Cl2NO/c22-19-9-6-15(12-20(19)23)21(25)13-24-17-7-8-18(24)11-16(10-17)14-4-2-1-3-5-14/h1-6,9,12,16-18,21,25H,7-8,10-11,13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for dopamine transporter was determined in rat striatal membrane.				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair
Vesicular acetylcholine transporter (Homo sapiens (Human))	BDBM50061251 (1-(3,4-Dichloro-phenyl)-2-(3-phenyl-8-aza-bicyclo[...) Show SMILES OC(CN1C2CCC1CC(C2)c1ccccc1)c1ccc(Cl)c(Cl)c1 |TLB:11:9:3:5.6| Show InChI InChI=1S/C21H23Cl2NO/c22-19-9-6-15(12-20(19)23)21(25)13-24-17-7-8-18(24)11-16(10-17)14-4-2-1-3-5-14/h1-6,9,12,16-18,21,25H,7-8,10-11,13H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding to vesicular acetylcholine transporter of torpedo synaptic vesicles				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061251 (1-(3,4-Dichloro-phenyl)-2-(3-phenyl-8-aza-bicyclo[...) Show SMILES OC(CN1C2CCC1CC(C2)c1ccccc1)c1ccc(Cl)c(Cl)c1 |TLB:11:9:3:5.6| Show InChI InChI=1S/C21H23Cl2NO/c22-19-9-6-15(12-20(19)23)21(25)13-24-17-7-8-18(24)11-16(10-17)14-4-2-1-3-5-14/h1-6,9,12,16-18,21,25H,7-8,10-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	249	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Sigma-1 binding assay was done in guinea pig membranes by labelling the binding site with [3H]-(+)-pentazocine				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair