BDBM50061259 1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-butanone::CHEMBL405524

SMILES: CN1CC2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccccc12

InChI Key: InChIKey=APDLVICBNVGZDB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061259 (1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H...) Show SMILES CN1CC2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C23H27FN2O/c1-25-17-23(20-5-2-3-6-21(20)25)12-15-26(16-13-23)14-4-7-22(27)18-8-10-19(24)11-9-18/h2-3,5-6,8-11H,4,7,12-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Sigma-1 binding assay was done in guinea pig membranes by labelling the binding site with [3H]-(+)-pentazocine				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair
Vesicular acetylcholine transporter (Homo sapiens (Human))	BDBM50061259 (1-(4-fluorophenyl)-4-[1-methylspiro[2,3-dihydro-1H...) Show SMILES CN1CC2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C23H27FN2O/c1-25-17-23(20-5-2-3-6-21(20)25)12-15-26(16-13-23)14-4-7-22(27)18-8-10-19(24)11-9-18/h2-3,5-6,8-11H,4,7,12-17H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding to vesicular acetylcholine transporter of torpedo synaptic vesicles				J Med Chem 40: 3905-14 (1998) Article DOI: 10.1021/jm970326r BindingDB Entry DOI: 10.7270/Q2KK99WJ
					More data for this Ligand-Target Pair