BDBM50061341 CHEMBL128222::[3-(4-Bromo-phenoxy)-propyl]-[2-(4-chloro-phenoxy)-ethyl]-amine

SMILES: Clc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1

InChI Key: InChIKey=PFKZREOHDYTZJM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50061341 (CHEMBL128222 | [3-(4-Bromo-phenoxy)-propyl]-[2-(4-...) Show SMILES Clc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C17H19BrClNO2/c18-14-2-6-16(7-3-14)21-12-1-10-20-11-13-22-17-8-4-15(19)5-9-17/h2-9,20H,1,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human dopamine receptor D4 expressed in CHO cells by displacement of [3H]-spiperone				J Med Chem 40: 4026-9 (1998) Article DOI: 10.1021/jm970422s BindingDB Entry DOI: 10.7270/Q22J69Z9
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50061341 (CHEMBL128222 | [3-(4-Bromo-phenoxy)-propyl]-[2-(4-...) Show SMILES Clc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C17H19BrClNO2/c18-14-2-6-16(7-3-14)21-12-1-10-20-11-13-22-17-8-4-15(19)5-9-17/h2-9,20H,1,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D4 was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50061341 (CHEMBL128222 | [3-(4-Bromo-phenoxy)-propyl]-[2-(4-...) Show SMILES Clc1ccc(OCCNCCCOc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C17H19BrClNO2/c18-14-2-6-16(7-3-14)21-12-1-10-20-11-13-22-17-8-4-15(19)5-9-17/h2-9,20H,1,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity against cloned human dopamine receptor D2 expressed in Chinese hamster ovary (CHO) K-1 cells by displacement of [3H]-spiperone.				J Med Chem 40: 4026-9 (1998) Article DOI: 10.1021/jm970422s BindingDB Entry DOI: 10.7270/Q22J69Z9
					More data for this Ligand-Target Pair