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SMILES: Nc1ncc(s1)-c1ccc2[nH]nc(-c3cnc4ccccc4c3)c2c1

InChI Key: InChIKey=GQCHSJRNLCGUAC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50061704 (CHEMBL3394059) Show SMILES Nc1ncc(s1)-c1ccc2[nH]nc(-c3cnc4ccccc4c3)c2c1 Show InChI InChI=1S/C19H13N5S/c20-19-22-10-17(25-19)12-5-6-16-14(8-12)18(24-23-16)13-7-11-3-1-2-4-15(11)21-9-13/h1-10H,(H2,20,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) using biotinylated-BAD peptide as substrate assessed as phosphorylation at serine 112 aft...				Bioorg Med Chem Lett 25: 775-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.091 BindingDB Entry DOI: 10.7270/Q2WQ05G8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50061704 (CHEMBL3394059) Show SMILES Nc1ncc(s1)-c1ccc2[nH]nc(-c3cnc4ccccc4c3)c2c1 Show InChI InChI=1S/C19H13N5S/c20-19-22-10-17(25-19)12-5-6-16-14(8-12)18(24-23-16)13-7-11-3-1-2-4-15(11)21-9-13/h1-10H,(H2,20,22)(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM3 (unknown origin) using biotinylated-BAD peptide as substrate assessed as phosphorylation at serine 112 aft...				Bioorg Med Chem Lett 25: 775-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.091 BindingDB Entry DOI: 10.7270/Q2WQ05G8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50061704 (CHEMBL3394059) Show SMILES Nc1ncc(s1)-c1ccc2[nH]nc(-c3cnc4ccccc4c3)c2c1 Show InChI InChI=1S/C19H13N5S/c20-19-22-10-17(25-19)12-5-6-16-14(8-12)18(24-23-16)13-7-11-3-1-2-4-15(11)21-9-13/h1-10H,(H2,20,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) using biotinylated-BAD peptide as substrate assessed as phosphorylation at serine 112 aft...				Bioorg Med Chem Lett 25: 775-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.091 BindingDB Entry DOI: 10.7270/Q2WQ05G8
					More data for this Ligand-Target Pair