BDBM50061784 CHEMBL542959::N-(3,5-Dichloro-phenyl)-N'-(3-ethyl-phenyl)-guanidine; hydrochloride

SMILES: CCc1cccc(NC(N)=Nc2cc(Cl)cc(Cl)c2)c1

InChI Key: InChIKey=DENVEWBSGVFMKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061784 (CHEMBL542959 | N-(3,5-Dichloro-phenyl)-N'-(3-ethyl...) Show SMILES CCc1cccc(NC(N)=Nc2cc(Cl)cc(Cl)c2)c1 |w:10.10| Show InChI InChI=1S/C15H15Cl2N3/c1-2-10-4-3-5-13(6-10)19-15(18)20-14-8-11(16)7-12(17)9-14/h3-9H,2H2,1H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair