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SMILES: Nc1nc(Cl)c2n(\C=C3\CC3CO)cnc2n1

InChI Key: InChIKey=JEHZGLCGANTAPF-DJWKRKHSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061982   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50061982
PNG
(CHEMBL75950 | {2-[1-(2-Amino-6-chloro-purin-7-yl)-...)
Show SMILES Nc1nc(Cl)c2n(\C=C3\CC3CO)cnc2n1
Show InChI InChI=1S/C10H10ClN5O/c11-8-7-9(15-10(12)14-8)13-4-16(7)2-5-1-6(5)3-17/h2,4,6,17H,1,3H2,(H2,12,14,15)/b5-2-
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UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Wayne State University School of Medicine

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...

J Med Chem 41: 10-23 (1998)


Article DOI: 10.1021/jm9705723
BindingDB Entry DOI: 10.7270/Q2VX0FM4
More data for this
Ligand-Target Pair