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BDBM50062053 6-(4-Fluoro-phenyl)-3-{4-[2-(2-methyl-imidazo[4,5-c]pyridin-1-yl)-ethyl]-piperazine-1-sulfonyl}-indole-1-carboxylic acid dimethylamide::CHEMBL133197

SMILES: CN(C)C(=O)n1cc(c2ccc(cc12)-c1ccc(F)cc1)S(=O)(=O)N1CCN(CCn2c(C)nc3cnccc23)CC1

InChI Key: InChIKey=MDKJGIHJFSFYBC-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062053   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50062053
PNG
(6-(4-Fluoro-phenyl)-3-{4-[2-(2-methyl-imidazo[4,5-...)
Show SMILES CN(C)C(=O)n1cc(c2ccc(cc12)-c1ccc(F)cc1)S(=O)(=O)N1CCN(CCn2c(C)nc3cnccc23)CC1
Show InChI InChI=1S/C30H32FN7O3S/c1-21-33-26-19-32-11-10-27(26)37(21)17-14-35-12-15-36(16-13-35)42(40,41)29-20-38(30(39)34(2)3)28-18-23(6-9-25(28)29)22-4-7-24(31)8-5-22/h4-11,18-20H,12-17H2,1-3H3
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Article
PubMed
 53n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes

J Med Chem 41: 74-95 (1998)


Article DOI: 10.1021/jm970389+
BindingDB Entry DOI: 10.7270/Q2MC8Z4D
More data for this
Ligand-Target Pair