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BDBM50062093 (4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-phenyl]-methanone::CHEMBL174859

SMILES: Cc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12

InChI Key: InChIKey=QWKNKKYJTUCXAB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062093   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50062093
PNG
((4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-im...)
Show SMILES Cc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12
Show InChI InChI=1S/C25H17FN4O/c1-3-16-5-4-6-21-24(16)19(12-28-21)25(31)17-7-8-18(20(26)11-17)14-30-15(2)29-22-13-27-10-9-23(22)30/h1,4-13,28H,14H2,2H3
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes


J Med Chem 41: 74-95 (1998)


Article DOI: 10.1021/jm970389+
BindingDB Entry DOI: 10.7270/Q2MC8Z4D
More data for this
Ligand-Target Pair