BDBM50062093 (4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-phenyl]-methanone::CHEMBL174859

SMILES: Cc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12

InChI Key: InChIKey=QWKNKKYJTUCXAB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50062093 ((4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-im...) Show SMILES Cc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12 Show InChI InChI=1S/C25H17FN4O/c1-3-16-5-4-6-21-24(16)19(12-28-21)25(31)17-7-8-18(20(26)11-17)14-30-15(2)29-22-13-27-10-9-23(22)30/h1,4-13,28H,14H2,2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair