BDBM50062095 4-Methyl-3-{2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl)-piperidin-1-yl]-acetyl}-indole-1-carboxylic acid dimethylamide::CHEMBL172484
SMILES: CN(C)C(=O)n1cc(C(=O)CN2CCC(CC2)n2c(C)nc3cnccc23)c2c(C)cccc12
InChI Key: InChIKey=JPNOFTWFUNXWBC-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet activating factor receptor (Cavia porcellus) | BDBM50062095 (4-Methyl-3-{2-[4-(2-methyl-imidazo[4,5-c]pyridin-1...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes | J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D | |||||||||||
More data for this Ligand-Target Pair |