BDBM50062276 CHEMBL55247::Phosphoric acid mono-[5-(6-ethylamino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl] ester
SMILES: CCNc1ncnc2n(cnc12)C1CC(OP(O)(O)=O)C(COP(O)(O)=O)O1
InChI Key: InChIKey=VFEOMJBNUNVQAO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 1 (Meleagris gallopavo) | BDBM50062276 (CHEMBL55247 | Phosphoric acid mono-[5-(6-ethylamin...) | MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Antagonist activity at P2Y1 receptor measured as capacity to inhibit 50% of phospholipase C stimulation elicited by 10 nM 2-MeSATP | J Med Chem 41: 183-90 (1998) Article DOI: 10.1021/jm970433l BindingDB Entry DOI: 10.7270/Q2SX6DWZ | |||||||||||
More data for this Ligand-Target Pair |