BDBM50062297 (R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-pyridin-4-yl-ethyl}-2-isobutyl-succinamide::CHEMBL302311

SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1ccncc1)C(=O)NCCc1ccc(O)cc1

InChI Key: InChIKey=LUZFASJCLDTWLF-TZIWHRDSSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062297 ((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1ccncc1)C(=O)NCCc1ccc(O)cc1 Show InChI InChI=1S/C24H32N4O5/c1-16(2)13-19(15-22(30)28-33)23(31)27-21(14-18-7-10-25-11-8-18)24(32)26-12-9-17-3-5-20(29)6-4-17/h3-8,10-11,16,19,21,29,33H,9,12-15H2,1-2H3,(H,26,32)(H,27,31)(H,28,30)/t19-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062297 ((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1ccncc1)C(=O)NCCc1ccc(O)cc1 Show InChI InChI=1S/C24H32N4O5/c1-16(2)13-19(15-22(30)28-33)23(31)27-21(14-18-7-10-25-11-8-18)24(32)26-12-9-17-3-5-20(29)6-4-17/h3-8,10-11,16,19,21,29,33H,9,12-15H2,1-2H3,(H,26,32)(H,27,31)(H,28,30)/t19-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50062297 ((R)-N*4*-Hydroxy-N*1*-{(R)-1-[2-(4-hydroxy-phenyl)...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](Cc1ccncc1)C(=O)NCCc1ccc(O)cc1 Show InChI InChI=1S/C24H32N4O5/c1-16(2)13-19(15-22(30)28-33)23(31)27-21(14-18-7-10-25-11-8-18)24(32)26-12-9-17-3-5-20(29)6-4-17/h3-8,10-11,16,19,21,29,33H,9,12-15H2,1-2H3,(H,26,32)(H,27,31)(H,28,30)/t19-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair