null

SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccco1

InChI Key: InChIKey=GNHMOHGVWISYSN-IERDGZPVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062332 ((R)-N*1*-[(S)-1-[(Furan-2-ylmethyl)-carbamoyl]-2-(...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccco1 Show InChI InChI=1S/C24H30N4O5/c1-15(2)10-16(12-22(29)28-32)23(30)27-21(24(31)26-14-18-6-5-9-33-18)11-17-13-25-20-8-4-3-7-19(17)20/h3-9,13,15-16,21,25,32H,10-12,14H2,1-2H3,(H,26,31)(H,27,30)(H,28,29)/t16-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50062332 ((R)-N*1*-[(S)-1-[(Furan-2-ylmethyl)-carbamoyl]-2-(...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccco1 Show InChI InChI=1S/C24H30N4O5/c1-15(2)10-16(12-22(29)28-32)23(30)27-21(24(31)26-14-18-6-5-9-33-18)11-17-13-25-20-8-4-3-7-19(17)20/h3-9,13,15-16,21,25,32H,10-12,14H2,1-2H3,(H,26,31)(H,27,30)(H,28,29)/t16-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062332 ((R)-N*1*-[(S)-1-[(Furan-2-ylmethyl)-carbamoyl]-2-(...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccco1 Show InChI InChI=1S/C24H30N4O5/c1-15(2)10-16(12-22(29)28-32)23(30)27-21(24(31)26-14-18-6-5-9-33-18)11-17-13-25-20-8-4-3-7-19(17)20/h3-9,13,15-16,21,25,32H,10-12,14H2,1-2H3,(H,26,31)(H,27,30)(H,28,29)/t16-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair