BDBM50062383 3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methoxy-benzamide::CHEMBL91571

SMILES: COc1ccc(cc1OC1CCCC1)C(=O)NCC(=O)NO

InChI Key: InChIKey=LPBBOFAPPVCKTQ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50062383 (3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...) Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)NCC(=O)NO Show InChI InChI=1S/C15H20N2O5/c1-21-12-7-6-10(15(19)16-9-14(18)17-20)8-13(12)22-11-4-2-3-5-11/h6-8,11,20H,2-5,9H2,1H3,(H,16,19)(H,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human Phosphodiesterase 4B				J Med Chem 41: 266-70 (1998) Article DOI: 10.1021/jm970685m BindingDB Entry DOI: 10.7270/Q2KD1X11
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50062383 (3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...) Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)NCC(=O)NO Show InChI InChI=1S/C15H20N2O5/c1-21-12-7-6-10(15(19)16-9-14(18)17-20)8-13(12)22-11-4-2-3-5-11/h6-8,11,20H,2-5,9H2,1H3,(H,16,19)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).				J Med Chem 41: 266-70 (1998) Article DOI: 10.1021/jm970685m BindingDB Entry DOI: 10.7270/Q2KD1X11
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50062383 (3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...) Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)NCC(=O)NO Show InChI InChI=1S/C15H20N2O5/c1-21-12-7-6-10(15(19)16-9-14(18)17-20)8-13(12)22-11-4-2-3-5-11/h6-8,11,20H,2-5,9H2,1H3,(H,16,19)(H,17,18)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4D				J Med Chem 41: 266-70 (1998) Article DOI: 10.1021/jm970685m BindingDB Entry DOI: 10.7270/Q2KD1X11
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50062383 (3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...) Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)NCC(=O)NO Show InChI InChI=1S/C15H20N2O5/c1-21-12-7-6-10(15(19)16-9-14(18)17-20)8-13(12)22-11-4-2-3-5-11/h6-8,11,20H,2-5,9H2,1H3,(H,16,19)(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4C				J Med Chem 41: 266-70 (1998) Article DOI: 10.1021/jm970685m BindingDB Entry DOI: 10.7270/Q2KD1X11
					More data for this Ligand-Target Pair