BDBM50062607 CHEMBL3397650

SMILES: Cc1cnc(Nc2ccc(cc2)C#N)nc1OCC(=O)Nc1ccccc1F

InChI Key: InChIKey=GESWXQKGWZUFIV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50062607 (CHEMBL3397650) Show SMILES Cc1cnc(Nc2ccc(cc2)C#N)nc1OCC(=O)Nc1ccccc1F Show InChI InChI=1S/C20H16FN5O2/c1-13-11-23-20(24-15-8-6-14(10-22)7-9-15)26-19(13)28-12-18(27)25-17-5-3-2-4-16(17)21/h2-9,11H,12H2,1H3,(H,25,27)(H,23,24,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 p66/p51 reverse transcriptase by spectrofluorometry				Bioorg Med Chem 23: 624-31 (2015) Article DOI: 10.1016/j.bmc.2014.11.032 BindingDB Entry DOI: 10.7270/Q2FF3V12
					More data for this Ligand-Target Pair