BDBM50062849 2,2-Dimethyl-3-(3,7,12-trimethyl-octadeca-3,7,11,15,17-pentaenyl)-oxirane::CHEMBL152597

SMILES: CC(CC\C=C\C=C)=CCCC=C(C)CCC=C(C)CCC1OC1(C)C

InChI Key: InChIKey=ZLFZRFFZFFSSEP-ZCGXPFLDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50062849 (2,2-Dimethyl-3-(3,7,12-trimethyl-octadeca-3,7,11,1...) Show SMILES CC(CC\C=C\C=C)=CCCC=C(C)CCC=C(C)CCC1OC1(C)C Show InChI InChI=1S/C25H40O/c1-7-8-9-10-14-21(2)15-11-12-16-22(3)17-13-18-23(4)19-20-24-25(5,6)26-24/h7-9,15-16,18,24H,1,10-14,17,19-20H2,2-6H3/b9-8+,21-15+,22-16+,23-18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Torino Curated by ChEMBL					Assay Description Compound was tested for inhibition of solubilized and partially purified Saccharomyces cerevisae Oxidosqualene-lanosterol cyclase				J Med Chem 41: 540-54 (1998) Article DOI: 10.1021/jm970534j BindingDB Entry DOI: 10.7270/Q2WQ02XV
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50062849 (2,2-Dimethyl-3-(3,7,12-trimethyl-octadeca-3,7,11,1...) Show SMILES CC(CC\C=C\C=C)=CCCC=C(C)CCC=C(C)CCC1OC1(C)C Show InChI InChI=1S/C25H40O/c1-7-8-9-10-14-21(2)15-11-12-16-22(3)17-13-18-23(4)19-20-24-25(5,6)26-24/h7-9,15-16,18,24H,1,10-14,17,19-20H2,2-6H3/b9-8+,21-15+,22-16+,23-18+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Torino Curated by ChEMBL					Assay Description Compound was tested for inhibition of solubilized and partially purified pig liver Oxidosqualene-lanosterol cyclase				J Med Chem 41: 540-54 (1998) Article DOI: 10.1021/jm970534j BindingDB Entry DOI: 10.7270/Q2WQ02XV
					More data for this Ligand-Target Pair