BDBM50063011 CHEMBL3398099

SMILES: Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)Nc3cccc(C)c3C)c2=O)c1

InChI Key: InChIKey=GGFWBLZIVVIIBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50063011 (CHEMBL3398099) Show SMILES Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)Nc3cccc(C)c3C)c2=O)c1 Show InChI InChI=1S/C23H25N3O3/c1-15-10-16(2)12-19(11-15)13-26-22(28)8-9-25(23(26)29)14-21(27)24-20-7-5-6-17(3)18(20)4/h5-12H,13-14H2,1-4H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Volgograd State Medical University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...				Bioorg Med Chem 23: 1069-81 (2015) Article DOI: 10.1016/j.bmc.2015.01.002 BindingDB Entry DOI: 10.7270/Q2RR20XW
					More data for this Ligand-Target Pair