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SMILES: COc1ccccc1NC(=O)NNc1nc2ccccc2c(=O)n1-c1cccc(OC(C)C)c1

InChI Key: InChIKey=WLCXEIALXDMICW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063645   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gastrin/cholecystokinin type B receptor


(MOUSE)		BDBM50063645
PNG
(CHEMBL9319 | N-(2-methoxyphenyl)-2-[3,4-dihydro-3-...)
Show SMILES COc1ccccc1NC(=O)NNc1nc2ccccc2c(=O)n1-c1cccc(OC(C)C)c1
Show InChI InChI=1S/C25H25N5O4/c1-16(2)34-18-10-8-9-17(15-18)30-23(31)19-11-4-5-12-20(19)26-24(30)28-29-25(32)27-21-13-6-7-14-22(21)33-3/h4-16H,1-3H3,(H,26,28)(H2,27,29,32)
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PubMed
n/an/a 10n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research

Curated by ChEMBL


Assay Description
Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligand

J Med Chem 41: 1042-9 (1998)


Article DOI: 10.1021/jm970373j
BindingDB Entry DOI: 10.7270/Q2TQ60N3
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50063645
PNG
(CHEMBL9319 | N-(2-methoxyphenyl)-2-[3,4-dihydro-3-...)
Show SMILES COc1ccccc1NC(=O)NNc1nc2ccccc2c(=O)n1-c1cccc(OC(C)C)c1
Show InChI InChI=1S/C25H25N5O4/c1-16(2)34-18-10-8-9-17(15-18)30-23(31)19-11-4-5-12-20(19)26-24(30)28-29-25(32)27-21-13-6-7-14-22(21)33-3/h4-16H,1-3H3,(H,26,28)(H2,27,29,32)
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PC sid
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Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research

Curated by ChEMBL


Assay Description
Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor from rat pancreas using [125I]-Bolton Hunter CCK-8 as radioligand

J Med Chem 41: 1042-9 (1998)


Article DOI: 10.1021/jm970373j
BindingDB Entry DOI: 10.7270/Q2TQ60N3
More data for this
Ligand-Target Pair