BDBM50063891 CHEMBL3403627
SMILES: OC(=O)CC1OCCn2c1cc1cc(OCc3ccc(OCF)c(c3)C(F)(F)F)ccc21
InChI Key: InChIKey=GSLSUMOITGVQKT-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50063891 (CHEMBL3403627) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay | Bioorg Med Chem Lett 25: 659-63 (2015) Article DOI: 10.1016/j.bmcl.2014.11.089 BindingDB Entry DOI: 10.7270/Q25T3N5P | |||||||||||
More data for this Ligand-Target Pair |