BDBM50063914 (R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-methyl)-2-phenethyl-succinamide::CHEMBL19623

SMILES: CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1

InChI Key: InChIKey=KEPYRBFIGNMAQF-MJGOQNOKSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50063914 ((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C21H25N3O4/c1-22-21(27)19(16-10-6-3-7-11-16)23-20(26)17(14-18(25)24-28)13-12-15-8-4-2-5-9-15/h2-11,17,19,28H,12-14H2,1H3,(H,22,27)(H,23,26)(H,24,25)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description Activity against Matrix metalloproteinase-9 (MMP-9).				J Med Chem 41: 1209-17 (1998) Article DOI: 10.1021/jm970404a BindingDB Entry DOI: 10.7270/Q2SQ8ZHB
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50063914 ((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C21H25N3O4/c1-22-21(27)19(16-10-6-3-7-11-16)23-20(26)17(14-18(25)24-28)13-12-15-8-4-2-5-9-15/h2-11,17,19,28H,12-14H2,1H3,(H,22,27)(H,23,26)(H,24,25)/t17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)				J Med Chem 41: 1209-17 (1998) Article DOI: 10.1021/jm970404a BindingDB Entry DOI: 10.7270/Q2SQ8ZHB
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063914 ((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C21H25N3O4/c1-22-21(27)19(16-10-6-3-7-11-16)23-20(26)17(14-18(25)24-28)13-12-15-8-4-2-5-9-15/h2-11,17,19,28H,12-14H2,1H3,(H,22,27)(H,23,26)(H,24,25)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description Activity against Matrix metalloproteinase-1 (MMP-1).				J Med Chem 41: 1209-17 (1998) Article DOI: 10.1021/jm970404a BindingDB Entry DOI: 10.7270/Q2SQ8ZHB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50063914 ((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C21H25N3O4/c1-22-21(27)19(16-10-6-3-7-11-16)23-20(26)17(14-18(25)24-28)13-12-15-8-4-2-5-9-15/h2-11,17,19,28H,12-14H2,1H3,(H,22,27)(H,23,26)(H,24,25)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46.3	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description Activity against Matrix metalloproteinase-2 (MMP-2).				J Med Chem 41: 1209-17 (1998) Article DOI: 10.1021/jm970404a BindingDB Entry DOI: 10.7270/Q2SQ8ZHB
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50063914 ((R)-N*4*-Hydroxy-N*1*-((S)-methylcarbamoyl-phenyl-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C21H25N3O4/c1-22-21(27)19(16-10-6-3-7-11-16)23-20(26)17(14-18(25)24-28)13-12-15-8-4-2-5-9-15/h2-11,17,19,28H,12-14H2,1H3,(H,22,27)(H,23,26)(H,24,25)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description Activity against Matrix metalloproteinase-3 (MMP-3).				J Med Chem 41: 1209-17 (1998) Article DOI: 10.1021/jm970404a BindingDB Entry DOI: 10.7270/Q2SQ8ZHB
					More data for this Ligand-Target Pair