BDBM50064104 (S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-3-methyl-butyric acid::CHEMBL36382

SMILES: CC(C)[C@H](NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O)C(O)=O

InChI Key: InChIKey=CQXKBNCQQAXWQI-GJZGRUSLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50064104 ((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C17H22FN2O6P/c1-11(2)15(17(22)23)20-16(21)14(19-10-27(24,25)26)9-5-7-12-6-3-4-8-13(12)18/h3-4,6,8,11,14-15,19H,9-10H2,1-2H3,(H,20,21)(H,22,23)(H2,24,25,26)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).				J Med Chem 41: 1513-23 (1998) Article DOI: 10.1021/jm970787c BindingDB Entry DOI: 10.7270/Q2PV6M1M
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50064104 ((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C17H22FN2O6P/c1-11(2)15(17(22)23)20-16(21)14(19-10-27(24,25)26)9-5-7-12-6-3-4-8-13(12)18/h3-4,6,8,11,14-15,19H,9-10H2,1-2H3,(H,20,21)(H,22,23)(H2,24,25,26)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibitory activity against neutral endopeptidase (NEP).				J Med Chem 41: 1513-23 (1998) Article DOI: 10.1021/jm970787c BindingDB Entry DOI: 10.7270/Q2PV6M1M
					More data for this Ligand-Target Pair