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SMILES: CCCOc1nc2sc(C)c(C)c2c(=O)o1

InChI Key: InChIKey=ZJAFVMZVKHJWBU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064314   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50064314
PNG
(5,6-Dimethyl-2-propoxy-thieno[2,3-d][1,3]oxazin-4-...)
Show SMILES CCCOc1nc2sc(C)c(C)c2c(=O)o1
Show InChI InChI=1S/C11H13NO3S/c1-4-5-14-11-12-9-8(10(13)15-11)6(2)7(3)16-9/h4-5H2,1-3H3
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Similars
Article
PubMed
 4.02n/an/an/an/a 0.0000628 1.56E+4n/an/a



University of Leipzig

Curated by ChEMBL


Assay Description
Steady state inhibition constant for Human Leukocyte Elastase inhibition

J Med Chem 41: 1729-40 (1998)


Article DOI: 10.1021/jm9708341
BindingDB Entry DOI: 10.7270/Q2QV3KNF
More data for this
Ligand-Target Pair