BDBM50064332 CHEMBL3403712

SMILES: CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc3OCOc3c2)ccc2c(cc(=O)oc12)C(F)(F)F

InChI Key: InChIKey=LTOQZEOGGXZELX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50064332 (CHEMBL3403712) Show SMILES CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc3OCOc3c2)ccc2c(cc(=O)oc12)C(F)(F)F Show InChI InChI=1S/C28H27F3N2O7/c1-3-6-18-20(10-8-17-19(28(29,30)31)14-23(34)40-24(17)18)37-12-5-4-11-33-25(35)27(2,32-26(33)36)16-7-9-21-22(13-16)39-15-38-21/h7-10,13-14H,3-6,11-12,15H2,1-2H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Kowa Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at Gal4-tagged LXRbeta (unknown origin) expressed in CHOK1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 1274-8 (2015) Article DOI: 10.1016/j.bmcl.2015.01.047 BindingDB Entry DOI: 10.7270/Q2CC12BH
					More data for this Ligand-Target Pair