BDBM50064432 CHEMBL3400160

SMILES: Fc1ccc(cc1)N1CCc2nc(COc3cccc(F)c3)cn2C1=O

InChI Key: InChIKey=XMDRLLZECSTZJY-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50064432 (CHEMBL3400160) Show SMILES Fc1ccc(cc1)N1CCc2nc(COc3cccc(F)c3)cn2C1=O Show InChI InChI=1S/C19H15F2N3O2/c20-13-4-6-16(7-5-13)23-9-8-18-22-15(11-24(18)19(23)25)12-26-17-3-1-2-14(21)10-17/h1-7,10-11H,8-9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Janssen Research and Development Curated by ChEMBL					Assay Description Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem Lett 25: 1310-7 (2015) Article DOI: 10.1016/j.bmcl.2015.01.038 BindingDB Entry DOI: 10.7270/Q2057HNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50064432 (CHEMBL3400160) Show SMILES Fc1ccc(cc1)N1CCc2nc(COc3cccc(F)c3)cn2C1=O Show InChI InChI=1S/C19H15F2N3O2/c20-13-4-6-16(7-5-13)23-9-8-18-22-15(11-24(18)19(23)25)12-26-17-3-1-2-14(21)10-17/h1-7,10-11H,8-9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Janssen Research and Development Curated by ChEMBL					Assay Description Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem Lett 25: 1310-7 (2015) Article DOI: 10.1016/j.bmcl.2015.01.038 BindingDB Entry DOI: 10.7270/Q2057HNQ
					More data for this Ligand-Target Pair