BDBM50064572 3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-benzothiazol-2-one::CHEMBL64167

SMILES: Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O

InChI Key: InChIKey=DGHMFEZDVIXRST-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards 5-hydroxytryptamine 2C receptor in membranes from pig choroid plexus using [3H]-N-methyl-mesulergine				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor (CALF)	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards Alpha-1A adrenergic receptor in membranes from bovine frontal cortex using [3H]-prazosin				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair
Serotonin 2a (5-HT2a) receptor (BOVINE)	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]-Ketanserin				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPAT				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]-raclopride				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50064572 (3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...) Show SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O Show InChI InChI=1S/C20H23N3OS/c1-21-18-8-7-16(15-19(18)25-20(21)24)9-10-22-11-13-23(14-12-22)17-5-3-2-4-6-17/h2-8,15H,9-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie Pharmaceutique Curated by ChEMBL					Assay Description Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HT				J Med Chem 41: 2010-8 (1998) Article DOI: 10.1021/jm970298c BindingDB Entry DOI: 10.7270/Q2FB522Q
					More data for this Ligand-Target Pair