BDBM50064777 6-amino-2-[2-(1H-3-indolyl)-1-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylcarboxamido-(1S)-ethylcarboxamido]hexanoic acid::CHEMBL70096
SMILES: NCCCCC(NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CC1)C=Cc1ccccc21)C(O)=O
InChI Key: InChIKey=OHXQRUJAVMZGBC-GEVKEYJPSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50064777 (6-amino-2-[2-(1H-3-indolyl)-1-spiro[1H-indene-1,4'...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human sst2 receptor expressed in CHO-K1 cells | J Med Chem 41: 2175-9 (1998) Article DOI: 10.1021/jm980194h BindingDB Entry DOI: 10.7270/Q2XW4KGS | |||||||||||
More data for this Ligand-Target Pair |