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BDBM50064958 CHEMBL309228::N-(1-Benzyl-piperidin-4-yl)-2-(3,4-dihydroxy-phenyl)-acetamide

SMILES: Oc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1O

InChI Key: InChIKey=TUTIDSUIVVDLTP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064958   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50064958
PNG
(CHEMBL309228 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4-...)
Show SMILES Oc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1O
Show InChI InChI=1S/C20H24N2O3/c23-18-7-6-16(12-19(18)24)13-20(25)21-17-8-10-22(11-9-17)14-15-4-2-1-3-5-15/h1-7,12,17,23-24H,8-11,13-14H2,(H,21,25)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Wake Forest University School of Medicine

Curated by ChEMBL


Assay Description
Compound tested for binding affinity towards sigma 1 receptor in quinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand.

J Med Chem 41: 2361-70 (1998)


Article DOI: 10.1021/jm980032l
BindingDB Entry DOI: 10.7270/Q2RN36Z5
More data for this
Ligand-Target Pair