BDBM50065213 1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxime::CHEMBL315676

SMILES: C#CCO\N=C1/CN2CCC1C2

InChI Key: InChIKey=NBYBORGTFLJPJT-MDZDMXLPSA-N

Data: 5 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50065213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M2				J Med Chem 41: 2524-36 (1998) Article DOI: 10.1021/jm960683m BindingDB Entry DOI: 10.7270/Q2VD6XKK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M1				J Med Chem 41: 2524-36 (1998) Article DOI: 10.1021/jm960683m BindingDB Entry DOI: 10.7270/Q2VD6XKK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human Muscarinic acetylcholine receptor M1 using [3H]-quinuclidinyl benzilate to label antagonist site (RQNB) in CHO cell...				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	890	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effective concentration for HMPA (human muscarinic inositol phosphate accumulation) activity measured in CHO cells expressing Muscarinic acetylcholin...				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human Muscarinic acetylcholine receptor M2 using [3H]-quinuclidinyl benzilate to label antagonist site (RQNB) in CHO cell...				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]cis-methyldioxolane binding to label agonist sites (RCMD) in rat neocortex				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50065213 (1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxi...) Show SMILES C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C9H12N2O/c1-2-5-12-10-9-7-11-4-3-8(9)6-11/h1,8H,3-7H2/b10-9+	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Effective concentration for MIPA (muscarinic-stimulated inositol phosphate accumulation) activity in SK-N-SH neuroblastoma cells expressing human mus...				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair