BDBM50065302 6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL87208

SMILES: Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

InChI Key: InChIKey=JFVLMRYDPQMRFA-XFFZJAGNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50065302 (6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...) Show SMILES Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C13H9FN2O/c14-8-3-4-10-11(7-9-2-1-5-15-9)13(17)16-12(10)6-8/h1-7,15H,(H,16,17)/b11-7-	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50065302 (6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...) Show SMILES Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C13H9FN2O/c14-8-3-4-10-11(7-9-2-1-5-15-9)13(17)16-12(10)6-8/h1-7,15H,(H,16,17)/b11-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50065302 (6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...) Show SMILES Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C13H9FN2O/c14-8-3-4-10-11(7-9-2-1-5-15-9)13(17)16-12(10)6-8/h1-7,15H,(H,16,17)/b11-7-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50065302 (6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...) Show SMILES Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C13H9FN2O/c14-8-3-4-10-11(7-9-2-1-5-15-9)13(17)16-12(10)6-8/h1-7,15H,(H,16,17)/b11-7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair