BDBM50065387 CHEBI:78886::E319

SMILES: CC(C)(C)c1cc(O)ccc1O

InChI Key: InChIKey=BGNXCDMCOKJUMV-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50065387 (CHEBI:78886 | E319) Show SMILES CC(C)(C)c1cc(O)ccc1O Show InChI InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gansu College of Traditional Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				Bioorg Med Chem Lett 25: 1476-8 (2015) Article DOI: 10.1016/j.bmcl.2015.02.028 BindingDB Entry DOI: 10.7270/Q21Z463X
					More data for this Ligand-Target Pair
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50065387 (CHEBI:78886 | E319) Show SMILES CC(C)(C)c1cc(O)ccc1O Show InChI InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.15E+4	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Induction of Nrf2-mediated ARE activity in human HepG2-ARE-C8 cells after 12 hrs by luciferase reporter gene assay				J Med Chem 56: 7925-38 (2013) Article DOI: 10.1021/jm400944k BindingDB Entry DOI: 10.7270/Q2Z322KJ
					More data for this Ligand-Target Pair
Pregnane X receptor (Homo sapiens (Human))	BDBM50065387 (CHEBI:78886 | E319) Show SMILES CC(C)(C)c1cc(O)ccc1O Show InChI InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
National Institutes of Health Chemical Genomics Center Curated by ChEMBL					Assay Description Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis				Drug Metab Dispos 39: 151-9 (2010) Article DOI: 10.1124/dmd.110.035105 BindingDB Entry DOI: 10.7270/Q2JS9S5P
					More data for this Ligand-Target Pair
Pregnane X receptor (Homo sapiens (Human))	BDBM50065387 (CHEBI:78886 | E319) Show SMILES CC(C)(C)c1cc(O)ccc1O Show InChI InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
National Institutes of Health Chemical Genomics Center Curated by ChEMBL					Assay Description Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assay				Drug Metab Dispos 39: 151-9 (2010) Article DOI: 10.1124/dmd.110.035105 BindingDB Entry DOI: 10.7270/Q2JS9S5P
					More data for this Ligand-Target Pair