BDBM50066350 3-Morpholin-4-yl-N-[4-(3-morpholin-4-yl-propionylamino)-9,10-dioxo-9,10-dihydro-anthracen-1-yl]-propionamide; hydrochloride::CHEMBL144827::CHEMBL544111

SMILES: O=C(CCN1CCOCC1)Nc1ccc(NC(=O)CCN2CCOCC2)c2C(=O)c3ccccc3C(=O)c12

InChI Key: InChIKey=FSMRMUDCRVGEFR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50066350 (3-Morpholin-4-yl-N-[4-(3-morpholin-4-yl-propionyla...) Show SMILES O=C(CCN1CCOCC1)Nc1ccc(NC(=O)CCN2CCOCC2)c2C(=O)c3ccccc3C(=O)c12 Show InChI InChI=1S/C28H32N4O6/c33-23(7-9-31-11-15-37-16-12-31)29-21-5-6-22(30-24(34)8-10-32-13-17-38-18-14-32)26-25(21)27(35)19-3-1-2-4-20(19)28(26)36/h1-6H,7-18H2,(H,29,33)(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of telomerase activity				J Med Chem 41: 3253-60 (1998) Article DOI: 10.1021/jm9801105 BindingDB Entry DOI: 10.7270/Q2TX3G1R
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50066350 (3-Morpholin-4-yl-N-[4-(3-morpholin-4-yl-propionyla...) Show SMILES O=C(CCN1CCOCC1)Nc1ccc(NC(=O)CCN2CCOCC2)c2C(=O)c3ccccc3C(=O)c12 Show InChI InChI=1S/C28H32N4O6/c33-23(7-9-31-11-15-37-16-12-31)29-21-5-6-22(30-24(34)8-10-32-13-17-38-18-14-32)26-25(21)27(35)19-3-1-2-4-20(19)28(26)36/h1-6H,7-18H2,(H,29,33)(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity of telomerase was measured using the TRAP assay.				J Med Chem 41: 4873-84 (1998) Article DOI: 10.1021/jm981067o BindingDB Entry DOI: 10.7270/Q2WW7GSD
					More data for this Ligand-Target Pair