BDBM50066447 1-Chloro-4-(3-chloro-4-ethoxy-benzylamino)-phthalazine-6-carbonitrile::CHEMBL112699

SMILES: CCOc1ccc(CNc2nnc(Cl)c3ccc(cc23)C#N)cc1Cl

InChI Key: InChIKey=OBTRBSIBSHNXGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50066447 (1-Chloro-4-(3-chloro-4-ethoxy-benzylamino)-phthala...) Show SMILES CCOc1ccc(CNc2nnc(Cl)c3ccc(cc23)C#N)cc1Cl Show InChI InChI=1S/C18H14Cl2N4O/c1-2-25-16-6-4-12(8-15(16)19)10-22-18-14-7-11(9-21)3-5-13(14)17(20)23-24-18/h3-8H,2,10H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from porcine platelets				J Med Chem 41: 3367-72 (1998) Article DOI: 10.1021/jm970815r BindingDB Entry DOI: 10.7270/Q2MS3RXG
					More data for this Ligand-Target Pair