BDBM50066448 (3-Chloro-4-methoxy-benzyl)-(4-chloro-7-trifluoromethyl-phthalazin-1-yl)-amine::CHEMBL114145

SMILES: COc1ccc(CNc2nnc(Cl)c3ccc(cc23)C(F)(F)F)cc1Cl

InChI Key: InChIKey=SYCABIFUKNTSKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50066448 ((3-Chloro-4-methoxy-benzyl)-(4-chloro-7-trifluorom...) Show SMILES COc1ccc(CNc2nnc(Cl)c3ccc(cc23)C(F)(F)F)cc1Cl Show InChI InChI=1S/C17H12Cl2F3N3O/c1-26-14-5-2-9(6-13(14)18)8-23-16-12-7-10(17(20,21)22)3-4-11(12)15(19)24-25-16/h2-7H,8H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from porcine platelets				J Med Chem 41: 3367-72 (1998) Article DOI: 10.1021/jm970815r BindingDB Entry DOI: 10.7270/Q2MS3RXG
					More data for this Ligand-Target Pair