BDBM50066451 (3-Chloro-4-methoxy-benzyl)-(4-chloro-7-nitro-phthalazin-1-yl)-amine::CHEMBL334291

SMILES: COc1ccc(CNc2nnc(Cl)c3ccc(cc23)[N+]([O-])=O)cc1Cl

InChI Key: InChIKey=SHCVFTMYELJHHC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50066451 ((3-Chloro-4-methoxy-benzyl)-(4-chloro-7-nitro-phth...) Show SMILES COc1ccc(CNc2nnc(Cl)c3ccc(cc23)[N+]([O-])=O)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O3/c1-25-14-5-2-9(6-13(14)17)8-19-16-12-7-10(22(23)24)3-4-11(12)15(18)20-21-16/h2-7H,8H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from porcine platelets				J Med Chem 41: 3367-72 (1998) Article DOI: 10.1021/jm970815r BindingDB Entry DOI: 10.7270/Q2MS3RXG
					More data for this Ligand-Target Pair