BDBM50066716 CHEMBL3403140

SMILES: Fc1ccc2c(c(sc2n1)S(=O)(=O)c1cccc(c1)C#N)-c1ccc(Cl)cc1

InChI Key: InChIKey=MYCQSKKGXJGMPW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50066716 (CHEMBL3403140) Show SMILES Fc1ccc2c(c(sc2n1)S(=O)(=O)c1cccc(c1)C#N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H10ClFN2O2S2/c21-14-6-4-13(5-7-14)18-16-8-9-17(22)24-19(16)27-20(18)28(25,26)15-3-1-2-12(10-15)11-23/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptor				Bioorg Med Chem Lett 25: 1724-9 (2015) Article DOI: 10.1016/j.bmcl.2015.02.073 BindingDB Entry DOI: 10.7270/Q2JS9S47
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50066716 (CHEMBL3403140) Show SMILES Fc1ccc2c(c(sc2n1)S(=O)(=O)c1cccc(c1)C#N)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H10ClFN2O2S2/c21-14-6-4-13(5-7-14)18-16-8-9-17(22)24-19(16)27-20(18)28(25,26)15-3-1-2-12(10-15)11-23/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assay				Bioorg Med Chem Lett 25: 1724-9 (2015) Article DOI: 10.1016/j.bmcl.2015.02.073 BindingDB Entry DOI: 10.7270/Q2JS9S47
					More data for this Ligand-Target Pair