BDBM50066773 (3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a]pyridine-3-carboxylic acid (4-guanidino-butyl)-amide; TFA::CHEMBL120162

SMILES: N[C@H]1CC[C@@H]2SC[C@H](N2C1=O)C(=O)NCCCCNC(N)=N

InChI Key: InChIKey=BKWDBVATEVWOQC-GUBZILKMSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin (Bos taurus (bovine))	BDBM50066773 ((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...) Show SMILES N[C@H]1CC[C@@H]2SC[C@H](N2C1=O)C(=O)NCCCCNC(N)=N Show InChI InChI=1S/C13H24N6O2S/c14-8-3-4-10-19(12(8)21)9(7-22-10)11(20)17-5-1-2-6-18-13(15)16/h8-10H,1-7,14H2,(H,17,20)(H4,15,16,18)/t8-,9-,10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Invitro inhibition was measured against Human bovine pancreatic trypsin.				J Med Chem 41: 3664-74 (1998) Article DOI: 10.1021/jm981013e BindingDB Entry DOI: 10.7270/Q22R3QSZ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50066773 ((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...) Show SMILES N[C@H]1CC[C@@H]2SC[C@H](N2C1=O)C(=O)NCCCCNC(N)=N Show InChI InChI=1S/C13H24N6O2S/c14-8-3-4-10-19(12(8)21)9(7-22-10)11(20)17-5-1-2-6-18-13(15)16/h8-10H,1-7,14H2,(H,17,20)(H4,15,16,18)/t8-,9-,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Invitro inhibition was measured against Human Thrombin.				J Med Chem 41: 3664-74 (1998) Article DOI: 10.1021/jm981013e BindingDB Entry DOI: 10.7270/Q22R3QSZ
					More data for this Ligand-Target Pair