BDBM50066829 CHEMBL3401610

SMILES: CCc1c([nH]c2ccc(Cl)cc12)C(=O)Nc1cccc(c1)-c1cccc(n1)N(C)C

InChI Key: InChIKey=YGIKSMCSADYGOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50066829 (CHEMBL3401610) Show SMILES CCc1c([nH]c2ccc(Cl)cc12)C(=O)Nc1cccc(c1)-c1cccc(n1)N(C)C Show InChI InChI=1S/C24H23ClN4O/c1-4-18-19-14-16(25)11-12-21(19)28-23(18)24(30)26-17-8-5-7-15(13-17)20-9-6-10-22(27-20)29(2)3/h5-14,28H,4H2,1-3H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55940-induced calcium mobilization incubated fo...				Bioorg Med Chem 23: 2195-203 (2015) Article DOI: 10.1016/j.bmc.2015.02.058 BindingDB Entry DOI: 10.7270/Q29888PG
					More data for this Ligand-Target Pair