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BDBM50067023 1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)-3,3-dimethylpiperidine::1-[3-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-3,3-dimethyl-piperidine::CHEMBL128996

SMILES: COc1ccc2C(CCCN3CCCC(C)(C)C3)CCCc2c1

InChI Key: InChIKey=CNWMIHRLRATNFI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067023   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(RAT)		BDBM50067023
PNG
(1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Show SMILES COc1ccc2C(CCCN3CCCC(C)(C)C3)CCCc2c1
Show InChI InChI=1S/C21H33NO/c1-21(2)12-6-14-22(16-21)13-5-9-17-7-4-8-18-15-19(23-3)10-11-20(17)18/h10-11,15,17H,4-9,12-14,16H2,1-3H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Università di Bari

Curated by ChEMBL


Assay Description
Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.

J Med Chem 41: 3940-7 (1998)


Article DOI: 10.1021/jm970692a
BindingDB Entry DOI: 10.7270/Q2NK3D5Q
More data for this
Ligand-Target Pair