BDBM50067325 CHEMBL3237083

SMILES: Fc1ccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)cc1

InChI Key: InChIKey=OBAURJSGVNPFAW-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50067325 (CHEMBL3237083) Show SMILES Fc1ccc(Nc2ncnc3scc(-c4ccc(Cl)cc4)c23)cc1 Show InChI InChI=1S/C18H11ClFN3S/c19-12-3-1-11(2-4-12)15-9-24-18-16(15)17(21-10-22-18)23-14-7-5-13(20)6-8-14/h1-10H,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Biology and Genetics NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...				Bioorg Med Chem 23: 2287-93 (2015) Article DOI: 10.1016/j.bmc.2014.12.044 BindingDB Entry DOI: 10.7270/Q2RB7692
					More data for this Ligand-Target Pair