BDBM50067339 CHEMBL1626011

SMILES: Oc1ccc(Nc2ncnc3scc(-c4ccccc4)c23)cc1

InChI Key: InChIKey=WHSNBBNHMCBXAR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50067339 (CHEMBL1626011) Show SMILES Oc1ccc(Nc2ncnc3scc(-c4ccccc4)c23)cc1 Show InChI InChI=1S/C18H13N3OS/c22-14-8-6-13(7-9-14)21-17-16-15(12-4-2-1-3-5-12)10-23-18(16)20-11-19-17/h1-11,22H,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Biology and Genetics NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...				Bioorg Med Chem 23: 2287-93 (2015) Article DOI: 10.1016/j.bmc.2014.12.044 BindingDB Entry DOI: 10.7270/Q2RB7692
					More data for this Ligand-Target Pair