BDBM50067479 2'-methyl-(2'S)-spiro[4-azabicyclo[2.2.1]heptane-2,4'-(dihydro[1,3]dioxolane)]::Azaspirodioxolane analogue::CHEMBL134830

SMILES: C[C@H]1OCC2(CN3CCC2C3)O1

InChI Key: InChIKey=BKWTWVOXJHEHBQ-UEJVZZJDSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50067479 (2'-methyl-(2'S)-spiro[4-azabicyclo[2.2.1]heptane-2...) Show SMILES C[C@H]1OCC2(CN3CCC2C3)O1 |TLB:3:4:10:8.7,THB:11:4:10:8.7| Show InChI InChI=1S/C9H15NO2/c1-7-11-6-9(12-7)5-10-3-2-8(9)4-10/h7-8H,2-6H2,1H3/t7-,8?,9?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Astra Arcus USA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic acetylcholine receptor using [3H]-OXO-M as the radioligand.				J Med Chem 41: 4181-5 (1998) Article DOI: 10.1021/jm980192x BindingDB Entry DOI: 10.7270/Q2PV6P3B
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50067479 (2'-methyl-(2'S)-spiro[4-azabicyclo[2.2.1]heptane-2...) Show SMILES C[C@H]1OCC2(CN3CCC2C3)O1 |TLB:3:4:10:8.7,THB:11:4:10:8.7| Show InChI InChI=1S/C9H15NO2/c1-7-11-6-9(12-7)5-10-3-2-8(9)4-10/h7-8H,2-6H2,1H3/t7-,8?,9?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50067479 (2'-methyl-(2'S)-spiro[4-azabicyclo[2.2.1]heptane-2...) Show SMILES C[C@H]1OCC2(CN3CCC2C3)O1 |TLB:3:4:10:8.7,THB:11:4:10:8.7| Show InChI InChI=1S/C9H15NO2/c1-7-11-6-9(12-7)5-10-3-2-8(9)4-10/h7-8H,2-6H2,1H3/t7-,8?,9?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair