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BDBM50067620 2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-(3-{methyl-[2-(3,4,5-trimethoxy-phenoxy)-ethyl]-amino}-propyl)-thiazolidin-4-one::CHEMBL137352

SMILES: COc1cc(OCCN(C)CCCN2C(SCC2=O)c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(OC)c1OC

InChI Key: InChIKey=LGXYJZXPHICFLX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067620   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium channel


(RAT)		BDBM50067620
PNG
(2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-(3-{methy...)
Show SMILES COc1cc(OCCN(C)CCCN2C(SCC2=O)c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(OC)c1OC
Show InChI InChI=1S/C32H48N2O6S/c1-31(2,3)23-16-21(17-24(28(23)36)32(4,5)6)30-34(27(35)20-41-30)13-11-12-33(7)14-15-40-22-18-25(37-8)29(39-10)26(19-22)38-9/h16-19,30,36H,11-15,20H2,1-10H3
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PC sid
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Similars
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of K+ induced contractions of the isolated rat aorta.

J Med Chem 41: 4309-16 (1998)


Article DOI: 10.1021/jm980335f
BindingDB Entry DOI: 10.7270/Q23N22JV
More data for this
Ligand-Target Pair