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BDBM50067633 2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-(3-dimethylamino-propyl)-thiazolidin-4-one::CHEMBL136357

SMILES: CN(C)CCCN1C(SCC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key: InChIKey=ZUQGTPHKMLMERI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067633   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium channel


(RAT)		BDBM50067633
PNG
(2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-(3-dimeth...)
Show SMILES CN(C)CCCN1C(SCC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C22H36N2O2S/c1-21(2,3)16-12-15(13-17(19(16)26)22(4,5)6)20-24(18(25)14-27-20)11-9-10-23(7)8/h12-13,20,26H,9-11,14H2,1-8H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of K+ induced contractions of the isolated rat aorta.

J Med Chem 41: 4309-16 (1998)


Article DOI: 10.1021/jm980335f
BindingDB Entry DOI: 10.7270/Q23N22JV
More data for this
Ligand-Target Pair