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BDBM50067638 3-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2-(3,5-di-tert-butyl-4-hydroxy-phenyl)-thiazolidin-4-one::CHEMBL335343

SMILES: CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C1SCC(=O)N1CCCN1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=JVOUSBDNKSHHNC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067638   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium channel


(RAT)		BDBM50067638
PNG
(3-[3-(4-Benzyl-piperidin-1-yl)-propyl]-2-(3,5-di-t...)
Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C1SCC(=O)N1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C32H46N2O2S/c1-31(2,3)26-20-25(21-27(29(26)36)32(4,5)6)30-34(28(35)22-37-30)16-10-15-33-17-13-24(14-18-33)19-23-11-8-7-9-12-23/h7-9,11-12,20-21,24,30,36H,10,13-19,22H2,1-6H3
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PC sid
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Similars
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of K+ induced contractions of the isolated rat aorta.

J Med Chem 41: 4309-16 (1998)


Article DOI: 10.1021/jm980335f
BindingDB Entry DOI: 10.7270/Q23N22JV
More data for this
Ligand-Target Pair