BDBM50067878 9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3-one::CHEMBL141623

SMILES: COc1c2ccoc2cc2oc(=O)cnc12

InChI Key: InChIKey=RHGCZKKDIWKZNK-UHFFFAOYSA-N

Data: 5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50067878 (9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...) Show SMILES COc1c2ccoc2cc2oc(=O)cnc12 Show InChI InChI=1S/C11H7NO4/c1-14-11-6-2-3-15-7(6)4-8-10(11)12-5-9(13)16-8/h2-5H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.90E+5	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak K+ currents against Kv1.2 gene				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50067878 (9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...) Show SMILES COc1c2ccoc2cc2oc(=O)cnc12 Show InChI InChI=1S/C11H7NO4/c1-14-11-6-2-3-15-7(6)4-8-10(11)12-5-9(13)16-8/h2-5H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak K+ currents against Kv1.5 gene				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50067878 (9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...) Show SMILES COc1c2ccoc2cc2oc(=O)cnc12 Show InChI InChI=1S/C11H7NO4/c1-14-11-6-2-3-15-7(6)4-8-10(11)12-5-9(13)16-8/h2-5H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak K+ currents against Kv3.1 gene				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50067878 (9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...) Show SMILES COc1c2ccoc2cc2oc(=O)cnc12 Show InChI InChI=1S/C11H7NO4/c1-14-11-6-2-3-15-7(6)4-8-10(11)12-5-9(13)16-8/h2-5H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak K+ currents against Kv1.1 gene				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.3 (Mus musculus)	BDBM50067878 (9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3...) Show SMILES COc1c2ccoc2cc2oc(=O)cnc12 Show InChI InChI=1S/C11H7NO4/c1-14-11-6-2-3-15-7(6)4-8-10(11)12-5-9(13)16-8/h2-5H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak Kv1.3 potassium currents				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
					More data for this Ligand-Target Pair