BDBM50067883 4-Hydroxy-4,6-dioxo-4lambda*5*-[1,4]azaphosphinane-2-carboxylic acid::CHEMBL336479

SMILES: OC(=O)C1NC(=O)CP(O)(O)=C1

InChI Key: InChIKey=JKBPVYOHNIYIDO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotase (Homo sapiens (Human))	BDBM50067883 (4-Hydroxy-4,6-dioxo-4lambda*5*-[1,4]azaphosphinane...) Show SMILES OC(=O)C1NC(=O)CP(O)(O)=C1 Show InChI InChI=1S/C5H8NO5P/c7-4-2-12(10,11)1-3(6-4)5(8)9/h1,3,10-11H,2H2,(H,6,7)(H,8,9)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
					More data for this Ligand-Target Pair