BindingDB PrimarySearch

BDBM50067892 4-Bromophenyl-boronic acid::4-bromo phenyl boronic acid::4-bromophenyl boronic acid::4-bromophenylboronic acid::Boronic acid derivative::CHEMBL20866

SMILES: OB(O)c1ccc(Br)cc1

InChI Key: InChIKey=QBLFZIBJXUQVRF-UHFFFAOYSA-N

Data: 10 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50067892
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-lactamase (Escherichia coli)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Medical School Curated by ChEMBL					Assay Description Inhibitory activity against E. coli AmpC beta-lactamase.				J Med Chem 41: 4577-86 (1998) Article DOI: 10.1021/jm980343w BindingDB Entry DOI: 10.7270/Q22N51FX
Northwestern University Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem Lett 19: 2642-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.147 BindingDB Entry DOI: 10.7270/Q27D2V4T
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Subtilisin BL (Bacillus lentus)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus				Bioorg Med Chem Lett 6: 2501-2506 (1996) Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem Lett 19: 2642-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.147 BindingDB Entry DOI: 10.7270/Q27D2V4T
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Candida albicans (Yeast))	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem Lett 19: 2642-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.147 BindingDB Entry DOI: 10.7270/Q27D2V4T
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Subtilisin BL (Bacillus lentus)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentus				Bioorg Med Chem Lett 6: 2501-2506 (1996) Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Subtilisin BL (Bacillus lentus)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus				Bioorg Med Chem Lett 6: 2501-2506 (1996) Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Subtilisin Carlsberg (Bacillus licheniformis)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentus				Bioorg Med Chem Lett 6: 2501-2506 (1996) Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli				Bioorg Med Chem Lett 4: 1229-1234 (1994) Article DOI: 10.1016/S0960-894X(01)80336-X BindingDB Entry DOI: 10.7270/Q2W9595N
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Urease (Glycine max (Soybean))	BDBM50067892 (4-Bromophenyl-boronic acid \| 4-bromo phenyl boroni...) Show SMILES OB(O)c1ccc(Br)cc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	2.20E+5	-5.19	n/a	n/a	n/a	n/a	n/a	7.0	37
Banaras Hindu University					Assay Description The inhibition studies of soybean urease were initiated with boric acid and boronic acids (butylboronic acid, 4-bromophenylboronic acid, and phenylbo...				J Enzyme Inhib Med Chem 25: 646-52 (2010) Article DOI: 10.3109/14756360903468155 BindingDB Entry DOI: 10.7270/Q2F18XM8
Banaras Hindu University					More data for this Ligand-Target Pair