BDBM50067930 4-[(E)-2-({1-[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-1H-pyrrol-2-ylmethyl}-carbamoyl)-vinyl]-N-methyl-benzamide; hydrochloride::CHEMBL553911

SMILES: CNC(=O)c1ccc(\C=C\C(=O)NCc2cccn2-c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1

InChI Key: InChIKey=URDMJJRPDWYCSP-GZTJUZNOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50067930 (4-[(E)-2-({1-[2,4-Dichloro-3-(2-methyl-quinolin-8-...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2cccn2-c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1 Show InChI InChI=1S/C33H28Cl2N4O3/c1-21-8-12-23-5-3-7-29(32(23)38-21)42-20-26-27(34)15-16-28(31(26)35)39-18-4-6-25(39)19-37-30(40)17-11-22-9-13-24(14-10-22)33(41)36-2/h3-18H,19-20H2,1-2H3,(H,36,41)(H,37,40)/b17-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Ltd. Curated by ChEMBL					Assay Description Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparations				J Med Chem 41: 4587-98 (1998) Article DOI: 10.1021/jm980330i BindingDB Entry DOI: 10.7270/Q2ZK5HBR
					More data for this Ligand-Target Pair
Bradykinin B2 receptor (Cavia porcellus)	BDBM50067930 (4-[(E)-2-({1-[2,4-Dichloro-3-(2-methyl-quinolin-8-...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCc2cccn2-c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1 Show InChI InChI=1S/C33H28Cl2N4O3/c1-21-8-12-23-5-3-7-29(32(23)38-21)42-20-26-27(34)15-16-28(31(26)35)39-18-4-6-25(39)19-37-30(40)17-11-22-9-13-24(14-10-22)33(41)36-2/h3-18H,19-20H2,1-2H3,(H,36,41)(H,37,40)/b17-11+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Ltd. Curated by ChEMBL					Assay Description Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparations				J Med Chem 41: 4587-98 (1998) Article DOI: 10.1021/jm980330i BindingDB Entry DOI: 10.7270/Q2ZK5HBR
					More data for this Ligand-Target Pair