BDBM50067932 (E)-N-({Methyl-[3-(2-methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-oxo-pyrrolidin-1-yl)-phenyl]-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide; hydrochloride::CHEMBL543685

SMILES: CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(N2CCCC2=O)c(COc2cccc3ccc(C)nc23)c1N1CCCC1=O

InChI Key: InChIKey=UQWMCHJPCGZRAA-RCCKNPSSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50067932 ((E)-N-({Methyl-[3-(2-methyl-quinolin-8-yloxymethyl...) Show SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(N2CCCC2=O)c(COc2cccc3ccc(C)nc23)c1N1CCCC1=O Show InChI InChI=1S/C41H42N6O6/c1-27-12-16-29-7-3-8-34(40(29)43-27)53-26-31-32(46-23-5-10-37(46)50)19-20-33(41(31)47-24-6-11-38(47)51)44(2)39(52)25-42-35(48)21-15-28-13-17-30(18-14-28)45-22-4-9-36(45)49/h3,7-8,12-21H,4-6,9-11,22-26H2,1-2H3,(H,42,48)/b21-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Ltd. Curated by ChEMBL					Assay Description Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparations				J Med Chem 41: 4587-98 (1998) Article DOI: 10.1021/jm980330i BindingDB Entry DOI: 10.7270/Q2ZK5HBR
					More data for this Ligand-Target Pair
Bradykinin B2 receptor (Cavia porcellus)	BDBM50067932 ((E)-N-({Methyl-[3-(2-methyl-quinolin-8-yloxymethyl...) Show SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(N2CCCC2=O)c(COc2cccc3ccc(C)nc23)c1N1CCCC1=O Show InChI InChI=1S/C41H42N6O6/c1-27-12-16-29-7-3-8-34(40(29)43-27)53-26-31-32(46-23-5-10-37(46)50)19-20-33(41(31)47-24-6-11-38(47)51)44(2)39(52)25-42-35(48)21-15-28-13-17-30(18-14-28)45-22-4-9-36(45)49/h3,7-8,12-21H,4-6,9-11,22-26H2,1-2H3,(H,42,48)/b21-15+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Ltd. Curated by ChEMBL					Assay Description Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparations				J Med Chem 41: 4587-98 (1998) Article DOI: 10.1021/jm980330i BindingDB Entry DOI: 10.7270/Q2ZK5HBR
					More data for this Ligand-Target Pair