BDBM50068222 CHEMBL3403322

SMILES: NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1

InChI Key: InChIKey=GPPIPJHLOJHQQU-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue non-specific alkaline phosphatase (TNAP) (Bos taurus (Cattle))	BDBM50068222 (CHEMBL3403322) Show SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C13H11FN2O3S/c14-10-6-4-9(5-7-10)13(17)16-11-2-1-3-12(8-11)20(15,18)19/h1-8H,(H,16,17)(H2,15,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...				Bioorg Med Chem 23: 2435-44 (2015) Article DOI: 10.1016/j.bmc.2015.03.054 BindingDB Entry DOI: 10.7270/Q2WW7KC8
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (IAP) (Bos taurus (Cattle))	BDBM50068222 (CHEMBL3403322) Show SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C13H11FN2O3S/c14-10-6-4-9(5-7-10)13(17)16-11-2-1-3-12(8-11)20(15,18)19/h1-8H,(H,16,17)(H2,15,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...				Bioorg Med Chem 23: 2435-44 (2015) Article DOI: 10.1016/j.bmc.2015.03.054 BindingDB Entry DOI: 10.7270/Q2WW7KC8
					More data for this Ligand-Target Pair
Tissue non-specific alkaline phosphatase (TNAP) (Bos taurus (Cattle))	BDBM50068222 (CHEMBL3403322) Show SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C13H11FN2O3S/c14-10-6-4-9(5-7-10)13(17)16-11-2-1-3-12(8-11)20(15,18)19/h1-8H,(H,16,17)(H2,15,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...				Bioorg Med Chem 23: 2435-44 (2015) Article DOI: 10.1016/j.bmc.2015.03.054 BindingDB Entry DOI: 10.7270/Q2WW7KC8
					More data for this Ligand-Target Pair