BDBM50068272 CHEMBL3403353

SMILES: CCn1c(NC2CCC2)nc2ccsc2c1=O

InChI Key: InChIKey=VLGHUVDPAFTFQM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50068272 (CHEMBL3403353) Show SMILES CCn1c(NC2CCC2)nc2ccsc2c1=O Show InChI InChI=1S/C12H15N3OS/c1-2-15-11(16)10-9(6-7-17-10)14-12(15)13-8-4-3-5-8/h6-8H,2-5H2,1H3,(H,13,14)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				Bioorg Med Chem Lett 25: 1910-4 (2015) Article DOI: 10.1016/j.bmcl.2015.03.031 BindingDB Entry DOI: 10.7270/Q2NC62VM
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50068272 (CHEMBL3403353) Show SMILES CCn1c(NC2CCC2)nc2ccsc2c1=O Show InChI InChI=1S/C12H15N3OS/c1-2-15-11(16)10-9(6-7-17-10)14-12(15)13-8-4-3-5-8/h6-8H,2-5H2,1H3,(H,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				Bioorg Med Chem Lett 25: 1910-4 (2015) Article DOI: 10.1016/j.bmcl.2015.03.031 BindingDB Entry DOI: 10.7270/Q2NC62VM
					More data for this Ligand-Target Pair